منابع مشابه
Transgenes, hypotheses, and hypertension.
In complex systems such as blood pressure homeostasis, physiological compensatory mechanisms effectively mask any perturbations to the status quo. When these mechanisms fail to restore homeostasis, the presenting phenotype may be far removed from the initial perturbation, making it difficult or even impossible to unravel the underlying etiology. This is the case with hypertensive rat models suc...
متن کاملTransgenes and their contributions to epigenetic research.
Shortly after gene transfer technologies had been established for different plant species, the first reports emerged about transgenes showing unexpected segregation patterns due to unstable expression. Initially, the erratic expression behavior of transgenes was considered a nuisance that impeded the impact and efficiency of a new technology. With the investigation of transgene silencing effect...
متن کاملThe Relation between Abductive Hypotheses and Inductive Hypotheses
In the AI eld, abduction is used for design, diagnosis and other tasks. This is because abduction is a sort of predictive inference. On the other hand, induction is used for classiication. For example, ILP nds greater tendencies in examples and learns general rules from the examples and background knowledge. Recently, the integration of abduction and induction has become a hot issue. In this pa...
متن کاملThe brain renin-angiotensin system contributes to the hypertension in mice containing both the human renin and human angiotensinogen transgenes.
We have previously shown that mice transgenic for both the human renin and human angiotensinogen genes (RA+) exhibit appropriate tissue- and cell-specific expression of both transgenes, have 4-fold higher plasma angiotensin II (AII) levels, and are chronically hypertensive. However, the relative contribution of circulating and tissue-derived AII in causing hypertension in these animals is not k...
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The problem of testing fuzzy hypotheses in the presence of vague data is considered. A new method based on the necessity index of strict dominance (NSD) is suggested. An example hoe to apply the proposed test in statistical quality control is shown.
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ژورنال
عنوان ژورنال: Hypertension
سال: 1994
ISSN: 0194-911X,1524-4563
DOI: 10.1161/01.hyp.23.4.428